Pediatric Advance Life Support: Pulseless Electrical Activity (PEA)

IV Access
·         Peripheral IV
·         Central line
·         Intraosseous
·         Intratracheal

Intraosseous (IO) Access
·         All intravenous medications can be administered intraosseously
·         Onset of action and drug levels are comparable to venous administration
·         IO access can be used to obtain blood samples for analysis
·         Use manual pressure or an infusion pump to administer viscous drugs or rapid fluid boluses
·         Follow each medication with a saline flush

Peripheral IVs
·         Placement may be difficult in a critically ill child
·         Central venous placement requires procedure can be time consuming

Endotracheal Drug Administration
·         Lipid-soluble drugs, such as lidocaine, epinephrine, atropine, and naloxone (mnemonic “LEAN”)
·         Effects may not be uniform with tracheal as compared with intravenous administration
·         Expert consensus recommends doubling or tripling the dose of lidocaine, atropine or naloxone
·         Epinephrine 0.1 mg/kg or 0.1 mL/kg of 1:1000 concentration is recommended

ET tube Medication Administration
·         Dilute the dose in 2 to 5 mL saline
·         Remove ambu bag from ET tube
·         Inject it into the ET tube
·         Replace ambu bag on ET tube
·         Administer 2 to 3 breaths with the ambu bag

Central IV Drug Delivery
                    Peak drug concentrations are higher and drug circulation times shorter
                    Central line placement can interrupt CPR.
                    A central line extending into the superior vena cava can be used to monitor ScvO2 and estimate CPP during CPR, both of which are predictive of ROSC

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