The Epinephrine Effect
The Effects of Epinephrine During a Pulseless Arrest Drug Therapy: Epinephrine · Epinephrine 1mg (1:10,000 solution) IV/IO q3-5min · ETT dose (1:1000 solution) 2mg diluted in 10cc of NS · Increases systemic vascular resistance (vasoconstriction) · Increase coronary and cerebral perfusion pressures during CPR · Escalating or high doses without demonstrable benefit · After drug delivery and approximately 5 cycles (or about 2 minutes) of CPR then recheck the rhythm Algorithms and dosages · Pulseless VF/VT Epinephrine 1mg (1:10,000 solution) IV/IO q3-5min · Asystole: Epinephrine 1mg (1:10,000 solution) IV/IO q3-5min · PEA: Epinephrine 1mg (1:10,000 solution) IV/IO q3-5min · Unstable bradycardia Epinephrine 2-10 mcg/min infusion The effects of epinephrine usually last about 3-5 minutes. Initially one may observe a ventricular tachycardia, wide complex tachycardia, or a
